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Amount of codeine in cough syrup





PROMETHAZINE WITH CODEINE COUGH SYRUP CV - DailyMed

02/09/2015
08:27 | Author: Sarah Gray

Amount of codeine in cough syrup
PROMETHAZINE WITH CODEINE COUGH SYRUP CV - DailyMed

Promethazine hydrochloride and codeine phosphate syrup is indicated for the Dosage of codeine SHOULD NOT BE INCREASED if cough fails to respond;.

Narcotic analgesics cause histamine release, which appears to be responsible for wheals or urticaria sometimes seen at the site of injection on parenteral administration. Histamine release may also produce dilation of cutaneous blood vessels, with resultant flushing of the face and neck, pruritus, and sweating.

Codeine may produce orthostatic hypotension in ambulatory patients.

Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as (±)-10- phenothiazine monohydrochloride.

Codeine may cause or aggravate constipation.

Concomitant use of other agents with anticholinergic properties should be undertaken with caution.

Administration of promethazine has been associated with reported cholestatic jaundice.

Because of the potential for promethazine to reverse epinephrine's vasopressor effect, epinephrine should NOT be used to treat hypotension associated with promethazine overdose.

Narcotic analgesics, including codeine, should be administered with caution and the initial dose reduced in patients with acute abdominal conditions, convulsive disorders, significant hepatic or renal impairment, fever, hypothyroidism, Addison's disease, ulcerative colitis, prostatic hypertrophy, in patients with recent gastrointestinal or urinary tract surgery, and in the very young or elderly or debilitated patients.

Narcotic analgesics, including codeine, exert their primary effects on the central nervous system and gastrointestinal tract.

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Amount of codeine in cough syrup
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