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Codeine for cough in children





Don39t give codeine to kids under 12, warns Health Canada Toronto

03/03/2015
02:15 | Author: Sarah Gray

Codeine for cough in children
Don39t give codeine to kids under 12, warns Health Canada Toronto

Deaths of children spark tough warning against using the painkiller, including cough medicines containing codeine.

Toronto.com: Best All-Day Breakfast.

It pointed out that ultrarapid metabolization of codeine was much more common in people of North African and Middle Eastern descent than Europeans.

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“This recommendation is based on very rare cases of serious side effects and deaths in children that have been attributed to codeine, when given directly to a child, or to babies from breast milk,” Health Canada said in its release.

Health Canada has issued a warning against giving codeine to children under 12.

The last warning from Health Canada about codeine and children was in 2008, when the government agency warned nursing mothers who metabolized the painkiller quickly not to use it.

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The Hospital for Sick Children stopped prescribing codeine for children a few years ago.

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FDA39s Latest Deadly Drug Codeine WhiteCoat39s Call Room

03/03/2015
12:10 | Author: Alex Watson

Codeine for cough in children
FDA39s Latest Deadly Drug Codeine WhiteCoat39s Call Room

I also did a PubMed search for “children codeine p450” and also “pediatric When my son was 2 they gave us cough syrup with codeine.

Trying to justify the FDA’s existence/budget? Getting a cut of the fees for approving the genetic testing? Getting fees for some new pain medication so that it can be approved for use in pediatric patients? Something just doesn’t make sense.

The point is to gradually eliminate “grandfathered” medications (and OTC medications in general). After all, if it’s medicine, then the FDA ought to be able to point to documentation showing it’s been tested, right?

Oh, and the FDA also notes that doctors can always perform “FDA approved” genetic testing to see if children have the gene responsible for rapid metabolism of codeine.

Get ready for more governmental regulation of opioids and maybe even some black box warnings added to the prescribing information for c0deine-containing drugs … just for everyone’s safety, of course.

I can’t help wonder what motivation the FDA has to issue this warning about 4 deaths in tens or even hundreds of millions of prescriptions that were hypothesized to have been caused by this mechanism.

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Codeine still prescribed for kids39 cough - The Clinical Advisor

03/03/2015
02:15 | Author: Sarah Gray

Codeine for cough in children
Codeine still prescribed for kids39 cough - The Clinical Advisor

Despite national recommendations against prescribing codeine for children, research suggests little decline in prescription rates.

Despite national recommendations against prescribing codeine for children, research suggests little decline in prescription rates.

Rates of codeine prescription were higher for children aged 8 to 12 years (odds ratio 1.42; 95% CI: 1.21-1.67) and among clinicians outside the northeast, researchers found.

To assess changes in pediatric codeine prescribing rates, the researchers performed a serial cross-sectional analysis of ED visits in the United States from 2001 to 2010 among a nationally representative sample of patients aged 3 to 17 years who participated in the National Hospital Ambulatory Medical Care Survey.

“Although there was a small decline in codeine prescription over 10 years, use for cough or URI did not decline after national guidelines recommending against its use,” Sunitha V.

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Codeine-containing liquid over-the-counter medicines. Drug Safety

03/03/2015
04:00 | Author: Alex Watson

Codeine for cough in children
Codeine-containing liquid over-the-counter medicines. Drug Safety

Risks and benefits of codeine as a cough suppressant (OTC) oral liquids containing codeine for the treatment of cough in children, based on.

Should not be used for cough under 18 years.

In February 2009, we announced a package of measures to ensure safer use of other over-the-counter (OTC) cough and cold medicines for children younger than age 12 years. The MHRA is working to improve the availability of high-quality, ethically researched and properly authorised medicines for children.

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Article citation: Drug Safety Update Oct 2010, vol 4 issue 3: H3.

The Commission on Human Medicines and its Paediatric Medicines Expert Advisory Group have advised that codeine-containing OTC liquid medicines should not be used for cough suppression in children and young people younger than age 18 years.

Further information on the review of the benefits and risks of OTC oral liquids containing codeine for the treatment of cough in children is available in a report available on our website.

All content is available under the Open Government Licence v3.0, except where otherwise stated.

Article date: October 2010.

Published: 11 October 2010.

Coughs and colds occur frequently in children, but they are self-limiting and rarely harmful if left untreated.

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