This medication is not usually used for ongoing coughs from smoking, asthma, other long-term breathing problems (e.g., emphysema ), or coughs with a lot of mucus unless directed by your doctor.
This product may cause serious mental/mood changes and very serious (rarely fatal) breathing problems. This product may contain codeine or dihydrocodeine. Codeine and dihydrocodeine are changed into strong narcotic drugs ( morphine or dihydromorphine) in your body. In some people this happens faster and more compley than usual, which increases the risk of very serious side effects. Get medical help right away if you notice any of the following: slow/shallow breathing, unusual drowsiness/difficulty waking up, confusion.
See also Warning section.
Before taking this medication, l your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
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A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling (especially of the face/ tongue /throat), severe dizziness, trouble breathing.
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Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as anxiety, restlessness, sweating, shaking, chills, nausea, vomiting, and diarrhea ) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediay.
If overdose is suspected, contact a poison control center or emergency room immediay. US residents can call their local poison control center at. Canada residents can call a provincial poison control center. Symptoms of overdose may include: confusion, cold/clammy skin, fast/irregular heartbeat, slow/shallow breathing, seizures, loss of consciousness.
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit the use of alcohol and certain other medications that cause drowsiness. (See also Drug Interactions.).
Some products that may interact with this drug include: other anticholinergic drugs (e.g., benztropine, belladonna alkaloids), beta blockers (e.g., metoprolol, atenolol), cimetidine, certain medications for high blood pressure (guanethidine, methyldopa, reserpine), narcotic antagonists (e.g., naltrexone, naloxone), tricyclic antidepressants (e.g., amitriptyline, desipramine).
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Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Giving more than the recommended dose or using this medication along with other cough-and-cold products has resulted in serious (even fatal) side effects, including slowed/stopped breathing. Talk to the doctor or pharmacist before giving other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). Do not use this product to make a child sleepy.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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Take this medication by mouth with or without food with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor. This medication can be taken with food if stomach upset occurs. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. The fluid will help loosen the mucus in your lungs.
If you are prescribed this medication on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Information last revised February 2014. 2014 First Databank, Inc.
This medication may interfere with certain urine laboratory tests (e.g., 5-HIAA levels, VMA levels, amylase/lipase levels), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
Dizziness, drowsiness, headache, upset stomach, nausea, constipation, nervousness, or trouble sleeping may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly.
l your doctor right away if you have any serious side effects, including: mental/mood changes (e.g., hallucinations), shaking, trouble urinating, weakness, fast/ irregular heartbeat.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
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If you are using the liquid form, use a medication-measuring device or spoon to carefully measure the prescribed dose. Do not use a household spoon because you may not get the correct dose. If your liquid form is a suspension, shake the bottle well before each dose.
Guaifenesin and decongestants are available in both prescription and nonprescription products. Check the labels on all your medications carefully to make sure you are not taking more than one product containing these ingredients.
This medicine may contain aspartame. If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist regarding the safe use of this medicine.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Rarely, abnormal drug-seeking behavior ( addiction ) is possible with this medication. Do not increase your dose, take it more frequently, or use it for a longer time than prescribed. Properly stop the medication when so directed.
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Do not share this medication with others. It is against the law.
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Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.
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Get medical help right away if you have any very serious side effects, including: seizure.
This medication may contain sugar and/or alcohol. Caution is advised if you have diabetes, alcohol dependence, or liver disease. Ask your doctor or pharmacist about the safe use of this product.
Older adults may be more sensitive to the side effects of this drug, especially confusion, dizziness, drowsiness, slow/shallow breathing, fast/irregular heartbeat, problems urinating, or trouble sleeping.
Dosage is based on your medical condition, age, and response to treatment.
The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also affect breathing or cause drowsiness. Therefore, l your doctor or pharmacist if you are taking other products such as alcohol, medicine for sleep or anxiety (such as alprazolam, diazepam, zolpidem), muscle relaxants, and narcotic pain relievers (such as codeine).
Before having surgery, l your doctor or dentist that you are taking this medication.
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GENERIC NAME(S): PSEUDOEPHEDRINE HCL/CODEINE PHOSPHATE/GUAIFENESIN.
Children may be more sensitive to the side effects of the narcotic cough suppressant, especially extreme sleepiness, confusion, or slow/shallow/noisy breathing. (See also Warning section.).
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Before using this medication, women of childbearing age should talk with their doctor(s) about the risks and benefits. l your doctor if you are pregnant or if you plan to become pregnant. During pregnancy, this medication should be used only when clearly needed. It may slightly increase the risk of birth defects if used during the first two months of pregnancy. Also, using it for a long time or in high doses near the expected delivery date may harm the unborn baby. To lessen the risk, take the smallest effective dose for the shortest possible time. l the doctor right away if you notice any symptoms in your newborn baby such as slow/shallow breathing, irritability, abnormal/persistent crying, vomiting, or diarrhea.
Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could affect your heart rate/blood pressure or cause drowsiness. Ask your pharmacist about using those products safely.
This combination medication is used to temporarily treat cough, chest congestion, and stuffy nose symptoms caused by the common cold, flu, or other breathing illnesses (e.g., sinusitis, bronchitis ). Guaifenesin is an expectorant that helps thin and loosen mucus in the lungs, making it easier to cough up the mucus. The decongestant helps relieve stuffy nose symptoms. This product also contains a narcotic cough suppressant ( antitussive ) that affects a certain part of the brain, reducing the urge to cough.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, this product is not recommended to treat cold symptoms in children younger than 6 years. Some products (including some long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.
When used for an extended time, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.
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This product may pass into breast milk. Consult your doctor before breastfeeding. Products that contain codeine or dihydrocodeine may rarely have undesirable effects on a nursing infant. l the doctor right away if your infant develops increased sleepiness, trouble breast-feeding, trouble breathing, or unusual limpness. If your product contains codeine or dihydrocodeine, discuss the risks and benefits with your doctor before breast-feeding.
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Products that contain codeine or dihydrocodeine should not be used in children after certain surgeries (including tonsil/ adenoid removal). Also, for children younger than 12 years, do not use codeine or dihydrocodeine to treat cough or pain unless specifically directed by the doctor. Some children are more sensitive to codeine or dihydrocodeine and have had very serious (rarely fatal) breathing problems such as slow/shallow breathing (see also Side Effects section). Talk with your doctor or pharmacist about the risks and benefits of this medication.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
In the US.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at.
Before using this medication, l your doctor or pharmacist your medical history, especially of: abdominal problems (e.g., chronic constipation, ileus, gallbladder disease, pancreatitis), adrenal gland problem (e.g., Addison's disease), blood vessel problems (e.g., Raynaud's disease, low blood flow to the brain/legs/hands), certain brain disorders (e.g., head injury, tumor, increased pressure in the brain), breathing problems (e.g., asthma, emphysema, sleep apnea), diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, mental/mood problems (e.g., depression, psychosis), thyroid problems (e.g., hyperthyroidism, hypothyroidism), trouble urinating (e.g., due to enlarged prostate), use/abuse of drugs/alcohol.
l your doctor if your condition persists for more than 1 week, if it worsens, or if it occurs with fever, rash, or persistent headache. These may be symptoms of a serious medical problem and should be checked by a doctor.