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Codeine and breastfeeding





Codeine use while Breastfeeding

6/9/2014
01:45 | Author: Sarah Gray

Codeine and breastfeeding
Codeine use while Breastfeeding

Advice for mothers using Codeine while breastfeeding. Includes possible effects on breastfed infants and lactation.

2. Willmann S, Edginton AN, Coboeken K et al. Risk to the breast-fed neonate from codeine treatment to the mother: a quantitative mechanistic modeling study. Clin Pharmacol Ther. 2009;86:634-43. PMID:

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A mother took codeine 60 mg with acetaminophen every 12 hours for 2 days postpartum, then codeine 30 mg every 12 hours for episiotomy pain.

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Codeine Warning for Breastfeeding Moms - WebMD

4/8/2014
03:50 | Author: Alex Watson

Codeine and breastfeeding
Codeine Warning for Breastfeeding Moms - WebMD

18, 2007 -- The FDA today warned breastfeeding mothers who take codeine for after-birth pain to carefully watch their babies for signs of.

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"This announcement today does not mean women who need pain medicine should not breastfeed," Woodcock said. "The benefits of breastfeeding are well documented.".

SOURCES: FDA news conference, Aug. 17, 2007 with Janet Woodcock, MD, deputy commissioner and chief medical officer, FDA. Sandra Kweder, MD, deputy director, office of new drugs, FDA.

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Guidelines for maternal codeine use during breastfeeding

12/17/2014
05:25 | Author: Sarah Gray

Codeine and breastfeeding
Guidelines for maternal codeine use during breastfeeding

What are some guidelines for the safe use of codeine during breastfeeding? ANSWER Motherisk has summarized recent scientific evidence into suggested.

Recent research from Motherisk suggests that codeine might not be safe for all breastfed infants, as in a minority of cases it might cause CNS depression and apnea.

Although codeine is widely used in North America 9 randomized studies comparing the use of codeine with various NSAIDs in laparotomy cases (ie abdominal surgery) failed to show codeine to be superior in pain relief.

A minority of mothers might convert more codeine to morphine in their bodies, putting their babies at risk of side effects or even death.

Published Motherisk Updates are available on the Canadian Family Physician website ( ) and also on the Motherisk website ( www.motherisk.org ).

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Safety of codeine during breastfeeding

10/16/2014
03:20 | Author: Alex Watson

Codeine and breastfeeding
Safety of codeine during breastfeeding

QUESTION Recently a newborn died from morphine poisoning when hismother used codeine while breastfeeding. Many patients receive codeine for postlabour.

Hepatic steatosis was investigated for medium-chain acyl-CoA dehydrogenase deficiency, which was ruled out. Other fatty acid oxidative disorders, organic acidemias, congenital adrenal hyperplasia, hypothyroidism, and galactosemia were also ruled out. Postmortem toxicologic testing using gas chromatography–mass spectrometry revealed a blood concentration of morphine at 70 ng/mL and acetaminophen at 5.9 μg/mL.

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A Review of Codeine Safety and Regulations for the Breastfeeding

8/15/2014
01:15 | Author: Sarah Gray

Codeine and breastfeeding
A Review of Codeine Safety and Regulations for the Breastfeeding

Although the American Academy of Pediatrics has classified codeine as a medication that is compatible with breastfeeding(), at a recent.

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The reason that the American Academy of Pediatrics recommends codeine as a safe drug for breastfeeding women is because in the general population, most women possess 2 functional copies of the gene that codes for the drug metabolizing, liver enzymes (CYP2D6). This genotype allows for the normal metabolism of codeine. However, there are two genetic subsets of individuals in whom codeine is not a preferred analgesic.

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