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Codeine in urine





The human urinary excretion pattern of morphine and codeine

8/15/2014
03:29 | Author: Ryan Brooks

Does morphine have codeine in it
The human urinary excretion pattern of morphine and codeine

The urinary excretion patterns of morphine and codeine in a number of individuals following consumption of morphine-based narcotic drugs.

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Concentrations of morphine and codeine in urine of heroin abusers

6/14/2014
05:18 | Author: Alex Watson

Codeine in urine
Concentrations of morphine and codeine in urine of heroin abusers

Leg Med (Tokyo). 1999 Sep;1(3):140-4. Concentrations of morphine and codeine in urine of heroin abusers. Moriya F, Chan KM, Hashimoto Y. We have.

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National Center for Biotechnology Information, U.S. National Library of Medicine 8600 Rockville Pike, Bethesda MD, 20894 USA.

We have measured concentrations of morphine, codeine and 6-monoacetylmorphine in urine of people admitted to the Los Angeles County + University of Southern California Medical Center. Of 60 patients positive for morphine and/or codeine, 10 were judged to be heroin abusers based on positive results for 6-monoacetylmorphine, a specific metabolite of heroin. In nine of these ten patients, 0.028-39.4 microg/ml free codeine and 0.070-307 microg/ml total codeine were detected along with 1.74-218 microg/ml of free morphine and 11.2-2870 microg/ml of total morphine; the morphine-to-codeine ratios were 3.65-228 and 2.27-207 for the free forms and total amounts of these opiates, respectively. In the one patient who was negative for codeine, the concentrations of free and total morphine were 0.114 and 2.22 microg/ml, respectively. Based on our data and literature data available, the following criteria are proposed for judging heroin use from the results of urinalysis, especially when no 6-monoacetylmorphine is detected: (1) a detectable amount of free morphine exists and the concentration of total morphine is higher than 10 microg/ml; (2) a detectable amount of codeine exists; and (3) the morphine-to-codeine ratio is higher than 2 for both the free forms and total amounts of these opiates.

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Study of urinary excretion of codeine and morphine after oral

4/13/2014
07:27 | Author: Tyler James

Codeine in urine
Study of urinary excretion of codeine and morphine after oral

Results of an investigation on the urinary excretion of codeine and morphine after oral ingestion of 1 mg.kg-1 b.w codeine are reported. The investigation run on.

Results of an investigation on the urinary excretion of codeine and morphine after oral ingestion of 1 mg.kg-1 b.w codeine are reported. The investigation run on seven clinically healthy subjects showed: low digestive absorption of codeine (# 20%); rapid biotransformation of codeine into morphine (first urines excreted after absorption); rapid disappearance of codeine from urines (#30 hrs); persistence of morphine alone (#68 hrs); rapid evolution of the codeine/morphine ratio (inversion of the ratio after #18 hrs); total elimination of morphine which can be greater than for codeine; very different half-life periods for codeine and morphine (5.1 and 13.6 hrs); no other codeine metabolites (nor-codeine and nor-morphine); very high individual variations; one subject with low activity of cytochrome P 450 dbl/buFL. Finally, in an epidemiological survey of drug addict behaviors and detection of drug addiction, it seems very difficult, may be even illusory and hazardous, to try and justify morphine found in urines (morphine, heroin, codeine, codethyline, pholcodine...) except in the very legitimate case where the ratio of urine concentrations of codeine and morphine is greater than one.

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Interpretation of Opiate Urine Drug Screens

2/12/2014
09:56 | Author: Hannah Ramirez

Does morphine have codeine in it
Interpretation of Opiate Urine Drug Screens

Urine drug testing is highly reliable, but false positives can rarely occur for some Codeine. 48 h. Heroin (detected as morphine). 48 h. Hydromorphone. 2-4 d.

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Screening of Morphine Codeine in Urine of Opioid Abusers by

10/21/2014
01:05 | Author: Sarah Gray

Does morphine have codeine in it
Screening of Morphine Codeine in Urine of Opioid Abusers by

Aim: one hundred urine samples of abusers were examined for the presence of alkaloid (TLC) procedure for the screening and confirmation of urinary codeine.

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